It’s fun because it combines two of his themes: geometrical interlocking critters and things coming to life off the page and then returning. I guess the stairs don’t do anything weird here (whoops 😳 ) but some of his other works feature stairs doing impossible things, like this one: http://www.mcescher.nl/Shopmain/Foto/Posters/e6.jpg
And yes, it does look as if drugs may have been involved somewhere. Either that, or this guy had some seriously bizarre dreams.